We believe the science of aging demands a new standard

The study of aging has gained substantial momentum, with extensive research, studies, and publications dedicated to this topic. A growing body of evidence suggests that supplementing a healthy lifestyle with nutraceuticals can significantly support cellular function and overall well-being. At Cleavia, we meticulously curate cutting-edge research to formulate nutraceuticals that promote long-term health and foster healthy aging.

The evolution of supplements is here


We all age inevitably.
Science is ingrained in our DNA.

We are driven by science and dedicated to longevity. Recent discoveries in animal models have revealed interventions that can slow down and even reverse aging. With a cutting-edge approach, scientists now use "biological age" as a benchmark to measure aging accurately. Our mission is to make decades of longevity science accessible to everyone, not just a select few.

Science is at the heart of what we do. We explore innovative interventions inspired by the latest animal model research to extend healthy human life. Our goal is to translate scientific findings into practical benefits for people looking to improve their well-being and live longer, healthier lives.

Traditional age measurements are limited. That's why we embrace the concept of biological age, which considers various biological markers to determine a person's true age, healthspan, and potential life expectancy. By understanding biological age, we can offer effective strategies for healthy aging and slowing the aging process.

Science is at the heart of what we do. We explore innovative interventions inspired by the latest animal model research to extend healthy human life. Our goal is to translate scientific findings into practical benefits for people looking to improve their well-being and live longer, healthier lives.

Traditional age measurements are limited. That's why we embrace the concept of biological age, which considers various biological markers to determine a person's true age, healthspan, and potential life expectancy. By understanding biological age, we can offer effective strategies for healthy aging and slowing the aging process.


The 12 Hallmarks of Aging interconnect, as revealed by recent scientific research

Genomic Instability
As cells divide and replicate over time, the genetic material (DNA) is subject to damage and mutations. Accumulated genomic instability can lead to cellular dysfunction and contribute to aging processes.
Telomere Attrition
Telomeres, protective caps at the ends of chromosomes, gradually shorten with each cell division. Telomere attrition limits the replicative capacity of cells and is associated with cellular aging.
Epigenetic Alterations
Changes in gene expression patterns occur with age, affecting cellular function and contributing to the aging process.
Loss of Proteostasis
Cells rely on precise protein folding and maintenance to function properly. With age, there is a decline in proteostasis, leading to protein aggregation and cellular dysfunction.
Deregulated Nutrient Sensing
Cellular nutrient-sensing pathways, such as mTOR AMPK and Sirtuin, can become dysregulated with age, influencing cellular metabolism and contributing to aging.
Mitochondrial Dysfunction
Mitochondria, the energy-producing organelles in cells, can experience dysfunction with age, leading to reduced energy production and increased production of harmful reactive oxygen species (ROS).
Cellular Senescence
Cellular senescence is a state in which cells lose their ability to divide and function properly. Accumulation of senescent cells can lead to inflammation and tissue dysfunction.
Stem Cell Exhaustion
With age, the regenerative capacity of stem cells declines, impacting tissue repair and maintenance.
Altered Intercellular Communication
Age-related changes in cell signaling and communication can disrupt tissue homeostasis and contribute to aging.
Compromised autophagy
Autophagy is essential for clearing damaged organelles and proteins in cells. When autophagy is compromised with age, these cellular components accumulate, contributing to aging and age-related diseases. Restoring autophagy has potential as a therapeutic approach for mitigating age-related decline.
Microbiome Dysbiosis
The microbiome is crucial for digestion, immune system function, protection against pathogens, metabolism, mental health, and drug metabolism. Dysbiosis can lead to various health issues, making it essential to understand and maintain a healthy microbiome for overall well-being.
Chronic low-grade inflammation, known as "inflammaging," can result from a sustained immune response, contributing to tissue damage and age-related diseases.

Product Science

Covotein Plant-based protein + collagen

Covotein, a science-based formula, harnesses the optimal synergies among its active components. Designed to promote collagen production, enhance collagen synthesis and absorption, deliver amino acids, provide potent antioxidants, reduce inflammation, and neutralize free radicals, each active ingredient has undergone extensive scientific studies to ensure its contribution to your body’s ideal absorption and the utilization of essential nutrients it provides. These combined effects contribute to anti-aging properties, effectively combating signs of aging and promoting a more youthful appearance and a rejuvenated sense of well-being.


Discover our science-based formulation

Protein is an essential macronutrient for life. It is a building block of every human cell and is involved in the vital biochemical functions of the human body. Covotein combines the synergistic benefits of two exceptional plant-based protein sources (Belgian pea protein and brown rice protein). This exclusive blend provides a complete spectrum of amino acids, including all nine essential amino acids. These vital building blocks are essential for the growth and maintenance of our cells and tissues, providing the necessary building blocks for cellular repair and regeneration. Collagen is a vital protein that contributes to the strength and elasticity of our skin, hair, nails, and connective tissues. Our formula indirectly supports collagen production by supplying the necessary building blocks, amino acids, and nutrients needed for collagen synthesis. It promotes healthy skin, hair, nails, supports weight management, muscle growth and repair, and overall well-being.

Ovoderm® eggshell membrane is a science-backed, natural, and chemical-free ingredient extracted from eggshells. The eggshell membrane in Covotein contains hyaluronic acid and elastin, making it a rich source of multi-collagen that includes collagen types I, V, and X. It activates and boosts your body’s collagen and elastin production, effectively reducing wrinkles and fine lines while protecting the skin from oxidative stress. It improves skin tone, increases elasticity and firmness, restores the skin barrier, and promotes hydration for a smoother and softer complexion. It enhances the skin’s natural radiance, improves the overall appearance and texture of the skin. Ovoderm® has undergone clinical studies that prove its efficacy in combating the main signs of skin aging. It has also been researched for its potential benefits in promoting joint health and cartilage regeneration.

Vitamin C is a vital nutrient that acts as a catalyst for collagen synthesis. It helps convert certain amino acids into collagen fibers, the building blocks that support the stability and absorption of collagen. Vitamin C also stimulates natural collagen production. By optimizing the conversion process, vitamin C ensures efficient collagen production, supporting the strength and elasticity of various tissues in the body.

Grape seed extract is a natural ingredient renowned for its collagen-protecting and skin-enhancing properties, contains powerful antioxidants called proanthocyanidins. These antioxidants play a crucial role in safeguarding collagen fibers from damage caused by harmful molecules called free radicals. By preserving the integrity of collagen, grape seed extract contributes to the maintenance of youthful skin, reduction in the appearance of wrinkles, and improvement in joint flexibility.

Coenzyme Q10 (CoQ10) is a vital compound naturally present in the body, including healthy skin cells. It serves as a crucial enzyme involved in multiple cellular functions. CoQ10 is renowned for its potential to reduce signs of skin aging, such as facial wrinkles. It plays a role in energy production, DNA replication and repair, and the synthesis of collagen—a protein responsible for the structural support of tissues, including the skin. By promoting collagen synthesis and regeneration, CoQ10 helps maintain firm and healthy skin, contributing to a more youthful appearance. Additionally, its antioxidant properties aid in neutralizing harmful free radicals, potentially reducing oxidative damage and further supporting skin health.

Astaxanthin is a carotenoid and red pigment found in algae. It is one of the most powerful antioxidants in nature, highly anti-inflammatory, reduces oxidative stress, protects skin from UV damage and enhances collagen production to smoothen fine lines and wrinkles and improve the overall appearance of the skin. With its unique molecular structure, Astaxanthin effectively combats free radicals, neutralizes oxidative damage, and promotes collagen synthesis. It also contributes to skin hydration, supports overall skin health, and further enhances the anti-aging effects of Covotein.

Age-Defying Vitality Supplement

Age-Defying Vitality is a clinically studied 8-in-1 supplement designed to target the root causes of aging and slow down the aging process. This science-based formula harnesses optimal synergies among its active components. Each active ingredient has undergone extensive study to ensure its contribution to your body’s ideal absorption and utilization of the essential nutrients it provides.


Discover our science-based formulation

Activates sirtuins, a family of proteins responsible for maintaining the epigenome, which may lead to potential health improvements and longevity.

A natural compound with senolytic properties, capable of targeting and eliminating senescent cells. These dysfunctional cells accumulate with age and contribute to various age-related issues. By removing these senescent cells, fisetin may potentially promote healthy aging and improve tissue function.

Helps maintain the health and function of cells throughout the body, which contributes to healthier aging at the cellular level. It also plays a fundamental role in synthesizing DNA, RNA, and proteins, essential processes for cellular growth and repair. These functions are vital for overall well-being and healthy aging.

Activates autophagy, leading to increased cellular recycling and clearance of cellular waste. By promoting autophagy, spermidine may help reduce the accumulation of cellular debris and improve cellular function.

Acts as a potent antioxidant, scavenging free radicals and reducing oxidative stress, which can protect cells from damage and slow down the aging process. Its anti-inflammatory properties may help combat inflammation, which is associated with various chronic diseases.

Acts as an antioxidant, protecting cells from oxidative damage caused by free radicals. Its antioxidant properties contribute to cellular health and may have potential anti-aging effects by reducing oxidative stress.


Immunomodulatory properties help the body defend against infections, promote a balanced immune response, and aid in the removal of senescent cells.

Calcium alpha-ketoglutarate is a compound that provides a key metabolite used by mitochondria to produce cellular energy. It is involved in the citric acid cycle, also known as the Krebs cycle or the tricarboxylic acid cycle, which is a central pathway for generating energy in the form of adenosine triphosphate (ATP) within the mitochondria of cells.

NMN Supplement

NMN (Nicotinamide Mononucleotide) is a molecule that has gained significant attention in the field of aging and longevity research. It is a precursor to Nicotinamide Adenine Dinucleotide (NAD+), a coenzyme that plays a critical role in various cellular processes, including energy metabolism and DNA repair. Here’s an overview of the role of NMN in aging and longevity:

NAD+ Decline: NAD+ levels naturally decline with age, contributing to various age-related health issues. This crucial molecule plays a pivotal role in enabling proteins and enzymes to function effectively, including sirtuins, which are responsible for maintaining the epigenome.

NMN as a Precursor: Nicotinamide Mononucleotide (NMN) undergoes enzymatic reactions in the body to convert into NAD+. When taken as a supplement, NMN is efficiently absorbed and exhibits greater stability in the gut lumen and bloodstream compared to other NAD+ boosters. Recent studies suggest that NMN is the most effective NAD+ booster for influencing the aging process. This is why renowned aging specialists like Harvard Professor David Sinclair choose to use NMN.

DNA Repair: NAD+ is intimately involved in DNA repair mechanisms, including DNA damage detection and DNA strand break repair. Maintaining these processes can help reduce the accumulation of DNA damage, which is associated with aging and age-related diseases.

Cellular Energy Production: NAD+ serves as a key player in the production of cellular energy, primarily in the form of ATP (adenosine triphosphate). Maintaining adequate NAD+ levels may support mitochondrial function and overall cellular energy production, which can decline with age.

Sirtuins and Epigenome Maintenance: Sirtuins are a highly conserved family of proteins that exert significant control over various cellular processes, including gene expression, metabolic regulation, and stress responses, all of which are associated with the aging process. NAD+ functions as an essential coenzyme for sirtuins, enabling these proteins to perform deacetylation reactions on target proteins, modulating gene expression, DNA repair, stress responses, and metabolic processes, and potentially contributing to longevity and cellular health.


Discover our science-based formulation

Our NMN is made of high-purity (>99%) NMN (nicotinamide mononucleotide), a powerful longevity ingredient. Each bottle contains 60 capsules of 250mg each. 
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